Recombinant Human Transforming Growth Factor – beta 2 (rHuTGF-beta2)

英文全名

Recombinant Human Transforming Growth Factor – beta 2 (rHuTGF-beta2)

英文别名

蛋白结构

Squence of Recombinant Human Transforming Growth Factor - beta 2

氨基酸序列

Accession

Gene ID

产品英文概述

来源

Mouse myeloma cell line, NS0

分子量

生物活性

Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. The ED50 for this effect is 0.025-0.25 ng/mL.

外观

Sterile Filtered White lyophilized (freeze-dried) powder.

配方

Lyophilized from 0.2 um filtered concentrated solution in 35 % Acetonitrile and 0.1 % TFA.

内毒素

Less than 0.1 EU/ug of rHuTGF-beta2 as determined by LAL method.

溶解说明

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile 4 mM HCl to a concentration of 0.1 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriately buffered solutions.

储存条件

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

参考资料

TGF-beta2 is a pleiotropic cytokine that regulates immune function, cellular proliferation, and epithelial-mesenchymal transition. It shows cross-species activity in the development of cardiac, lung, craniofacial, limb, eye, ear, and urogenital systems. Latent TGF-beta is activated by proteolytic cleavage of the mature cytokine from the latency-associated peptide. TGF-beta2 signaling involves the accessory receptor Betaglycan, TGF-beta RII, and a type I TGF-beta receptor, resulting in the activation of Smad signal transduction.

纯度

> 97 % by SDS-PAGE analyses.

SDS-PAGE电泳

SDS-PAGE of Recombinant Human Transforming Growth Factor - beta 2

包装规格

5ug/100ug

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品牌链接

Recombinant Human Transforming Growth Factor – beta 2是ChemWhat品牌授权产品并通过沃尔森销售,下面是ChemWhat上的该产品链接 Recombinant Human Transforming Growth Factor – beta 2 (rHuTGF-beta2)