Recombinant Murine Monocyte Chemotactic Protein-2/CCL8 (rMuMCP-2/CCL8)

英文全名

Recombinant Murine Monocyte Chemotactic Protein-2/CCL8 (rMuMCP-2/CCL8)

英文别名

Small-inducible Cytokine A8

蛋白结构

Squence of Recombinant Murine Monocyte Chemotactic Protein-2/CCL8

氨基酸序列

GPDKAPVTCC FHVLKLKIPL RVLKSYERIN NIQCPMEAVV FQTKQGMSLC VDPTQKWVSE YMEILDQKSQ ILQP

Accession

Q9Z121

Gene ID

20307

产品英文概述

Murine CCL8, also known as monocyte chemotactic protein 2 (MCP-2), is belonging to the CC chemokine family and is encoded by the gene CCL8 in mouse. MCP-2 has two homogeneous MCP-1 (CCL2) and MCP-3 (CCL7). These three MCPs were found by IL-1-beta triggered human MG-63 osteosarcoma cells. CCL8 shares 62 % amino acid sequence identity with MCP-1, and shares 58 % amino acid sequence identity with MCP-2. CCL8 has chemotactic fuction for monocytes, eosinophils and neutrophils. In addition, it can also chemoattract activated NK cells.

来源

Escherichia coli.

分子量

Approximately 8.5 kDa, a single, non-glycosylated polypeptide chain containing 74 amino acids.

生物活性

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 10-100 ng/ml.

外观

Sterile filtered white lyophilized (freeze-dried) powder.

配方

Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl.

内毒素

Less than 1 EU/ug of rMuMCP-2/CCL8 as determined by LAL method.

溶解说明

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

储存条件

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

参考资料

纯度

> 97 % by SDS-PAGE and HPLC analyses.
SDS-PAGE of Recombinant Murine Monocyte Chemotactic Protein-2/CCL8

包装规格

5ug/100ug/500ug

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品牌链接

Recombinant Murine Monocyte Chemotactic Protein-2/CCL8是ChemWhat品牌授权产品并通过沃尔森销售,下面是ChemWhat上的该产品链接Recombinant Murine Monocyte Chemotactic Protein-2/CCL8 (rMuMCP-2/CCL8)