Recombinant Human Angiostatin (rHuAngiostatin)
英文全名
Recombinant Human Angiostatin (rHuAngiostatin)
英文别名
蛋白结构
氨基酸序列
VYLSECKTGN GKNYRGTMSK TKNGITCQKW SSTSPHRPRF SPATHPSEGL EENYCRNPDN DPQGPWCYTT DPEKRYDYCD ILECEEECMH CSGENYDGKI SKTMSGLECQ AWDSQSPHAH GYIPSKFPNK NLKKNYCRNP DRELRPWCFT TDPNKRWELC DIPRCTTPPP SSGPTYQCLK GTGENYRGNV AVTVSGHTCQ HWSAQTPHTH NRTPENFPCK NLDENYCRNP DGKRAPWCHT TNSQVRWEYC KIPSCDSSP
Accession
Gene ID
产品英文概述
来源
Escherichia coli.
分子量
Approximately 29.7 KDa, a single non-glycosylated polypeptide chain containing 259 amino acids.
生物活性
Fully biologically active when compared to standard. The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells in vitro and anti-angiogenesis in vivo is 5.5 × 105 IU/mg.
外观
Sterile filtered white lyophilized (freeze-dried) powder.
配方
Lyophilized from a 0.2 um filtered concentrated solution in 20 mM NaAc, pH 5.5, 4 % mannitol.
内毒素
Less than 1 EU/ug of rHuAngiostatin as determined by LAL method.
溶解说明
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
参考资料
1. Takahashi S, Shinya T, Sugiyama A. 2010. J Pharmacol Sci, 112: 432-7.2. Frank KFandMuller-Ehmsen J. 2009. Heart, 95: 269-70.3. Perri SR, Annabi B, Galipeau J. 2007. FASEB J, 21: 3928-36.4. Kim KS, Kim HS, Park JS, et al. 2004. Cancer Gene Ther, 11: 441-9.5. Wahl ML, Owen CS, Grant DS. 2002. Endothelium, 9: 205-16.
纯度
> 95 % by SDS-PAGE and HPLC analyses.
SDS-PAGE电泳
包装规格
10ug/100ug/500ug
安全数据表下载 (SDS)
技术参数表下载 (TDS)
品牌链接
Recombinant Human Angiostatin是ChemWhat品牌授权产品并通过沃尔森销售，下面是ChemWhat上的该产品链接 Recombinant Human Angiostatin (rHuAngiostatin)
